Sandbox Reserved 350: Difference between revisions
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<big><ins>'''The Three Loops'''</ins></big><ref name="Pubmed"/> | <big><ins>'''The Three Loops'''</ins></big><ref name="Pubmed"/> | ||
<br /> | <br /> | ||
*Apex | *'''Apex 1'''—<font color='purple'>'''Ser21-Trp31;''' containing Indole moieties able to form hydrogen bonds (Involving two consecutive Trp 26 & 27). </font> | ||
*Apex | *'''Apex 2'''—<font color='lightseagreen'>'''Asn39-Asn45;''' capped with a basic residue able to form hydrogen bonds (Arg43). </font> | ||
*Apex | *'''Apex 3'''—<font color='deeppink'>'''Gly75-Tyr84;''' Hydrophobic Loop (Leu79). </font> | ||
<br /> | <br /> | ||
The apexes of these <font color='orangered'> '''three loops''' </font> within the C2 domain, are able to create a deep groove lined by '''hydrophobic''' <font color='brown'> '''(Trp31, Met83)''' </font> and '''polar residues''' <font color='royalblue'> '''(Gln48, Ser78)'''</font>, as seen and consisting the '''"Open Form"''' of FVa-C2. This groove is seen as the primary membrane-binding site of the C2-Domain. <ref name="Pubmed"/> Link to Function.. maybe? | The apexes of these <font color='orangered'> '''three loops''' </font> within the C2 domain, are able to create a deep groove lined by '''hydrophobic''' <font color='brown'> '''(Trp31, Met83)''' </font> and '''polar residues''' <font color='royalblue'> '''(Gln48, Ser78)'''</font>, as seen and consisting the '''"Open Form"''' of FVa-C2. This groove is seen as the primary membrane-binding site of the C2-Domain. <ref name="Pubmed"/> Link to Function.. maybe? | ||
