Sandbox Reserved 328: Difference between revisions
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==Other information== | ==Other information== | ||
===Domain swapping=== | ===Domain swapping=== | ||
Domains 1 and 2 show high similarity in their cores, in a structural way rather than having large amounts of residues in common<ref name="1kar" />. This is also evident in the presense of hydrophobic residues forming the core of the domains. | |||
===Domain Swapping=== | |||
Dimer formation most likely involves swapping of domains 3 and 4 between the two monomers, which explains the large amount of surface area (approximately 90%) buried upon dimerization. This type of domain swapping has been observed in other proteins as well<ref name="swap"> PMID:8580836 </ref>. | |||
<ref name="1kar"> PMID:11842181 </ref>. | <ref name="1kar"> PMID:11842181 </ref>. | ||
