3o50: Difference between revisions
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{{STRUCTURE_3o50| PDB=3o50 | SCENE= }} | {{STRUCTURE_3o50| PDB=3o50 | SCENE= }} | ||
===Crystal structure of benzamide 9 bound to AuroraA=== | ===Crystal structure of benzamide 9 bound to AuroraA=== | ||
{{ABSTRACT_PUBMED_20684549}} | {{ABSTRACT_PUBMED_20684549}} | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020684549</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Huang, X.]] | [[Category: Huang, X.]] | ||
[[Category: Auroraa]] | |||
[[Category: Kinase domain]] | |||
[[Category: Transferase]] | |||
Revision as of 12:02, 24 April 2013
Crystal structure of benzamide 9 bound to AuroraA
Template:ABSTRACT PUBMED 20684549
About this Structure
3o50 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cee VJ, Schenkel LB, Hodous BL, Deak HL, Nguyen HN, Olivieri PR, Romero K, Bak A, Be X, Bellon S, Bush TL, Cheng AC, Chung G, Coats S, Eden PM, Hanestad K, Gallant PL, Gu Y, Huang X, Kendall RL, Lin MH, Morrison MJ, Patel VF, Radinsky R, Rose PE, Ross S, Sun JR, Tang J, Zhao H, Payton M, Geuns-Meyer SD. Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor. J Med Chem. 2010 Aug 4. PMID:20684549 doi:10.1021/jm100394y