2uz9: Difference between revisions
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[[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true" | [[Image:2uz9.jpg|left|200px]]<br /><applet load="2uz9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2uz9, resolution 2.30Å" /> | caption="2uz9, resolution 2.30Å" /> | ||
'''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT | '''HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.'''<br /> | ||
==Disease== | |||
Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2G OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 2K OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]], Charcot-Marie-Tooth disease, type 4A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606598 606598]] | |||
==About this Structure== | ==About this Structure== | ||
2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional | 2UZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=XAN:'>XAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn Binding Site For Residue A 1452'>AC1</scene> and <scene name='pdbsite=AC2:Xan Binding Site For Residue A 1453'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZ9 OCA]. | ||
[[Category: Guanine deaminase]] | [[Category: Guanine deaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 31 11:00:36 2008'' | ||
Revision as of 09:00, 31 January 2008
|
HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.
Disease
Known diseases associated with this structure: Charcot-Marie-Tooth disease, mixed axonal and demyelinating type OMIM:[606598], Charcot-Marie-Tooth disease, type 2G OMIM:[606598], Charcot-Marie-Tooth disease, type 2K OMIM:[606598], Charcot-Marie-Tooth disease, type 4A OMIM:[606598]
About this Structure
2UZ9 is a Single protein structure of sequence from Homo sapiens with ZN and XAN as ligands. Active as Guanine deaminase, with EC number 3.5.4.3 Known structural/functional Sites: AC1 and AC2. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Jan 31 11:00:36 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Guanine deaminase
- Homo sapiens
- Single protein
- Arrowsmith, C.
- Berglund, H.
- Busam, R.
- Collins, R.
- Dahlgren, L.G.
- Edwards, A.
- Flodin, S.
- Flores, A.
- Graslund, S.
- Hallberg, B.M.
- Hammarstrom, M.
- Holmberg-Schiavone, L.
- Johansson, I.
- Kallas, A.
- Karlberg, T.
- Kotenyova, T.
- Lehtio, L.
- Moche, M.
- Nordlund, P.
- Nyman, T.
- Ogg, D.
- Persson, C.
- Sagemark, J.
- Sgc, Structural.Genomics.Consortium.
- Stenmark, P.
- Sundstrom, M.
- Thorsell, A.G.
- Van-Den-Berg, S.
- Weigelt, J.
- Welin, M.
- XAN
- ZN
- Guanine aminohydrolase
- Hydrolase
- Purine metabolism
- Zinc
