MT1-MMP-TIMP-1 complex: Difference between revisions

<scene name='MT1-MMP-TIMP-1_complex/Cv/9'>Membrane type-1 matrix metalloproteinase (MT1-MMP)</scene> <font color='magenta'><b>(magenta)</b></font> forms complex with <scene name='MT1-MMP-TIMP-1_complex/Cv/10'>tissue inhibitor of metalloproteinase-1 (TIMP-1)</scene> <font color='orange'><b>(orange)</b></font>. <scene name='MT1-MMP-TIMP-1_complex/Cv/11'>The WT-TIMP binding interface</scene> <font color='cyan'><b>(cyan)</b></font> is mainly composed of the N-terminal segment that approaches the active site, the AB loop (Thr33-Tyr35), the CD loop (Ala65-Cys70), and the EF loop (Thr97-Ser100). The pivotal residue, threonine 98 (Thr98), is shown as red sticks.