Sandbox11: Difference between revisions

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¤Acetylcholinesterase (AChE) is a tetramer that is connected to the membrane in neuromuscular junctions by a molecule called collagen Q. [[http://www.ncbi.nlm.nih.gov/pubmed/11804574]]
¤Acetylcholinesterase (AChE) is a tetramer that is connected to the membrane in neuromuscular junctions by a molecule called collagen Q. [[http://www.ncbi.nlm.nih.gov/pubmed/11804574]]


¤In the <scene name='Sandbox11/Secondary_structure/1'>secondary structure</scene>, it can be seen that there are 17 alpha helices and 14 beta strands.  There  are 2 beta sheets formed from 3 anti-parallel and 11 anti-parallel beta sheets, respectively(maybe highlight with green scene).  
¤Acetylcholinesterase (AChE) is an monomeric enzyme.  Most often, AChE forms a tetramer and binds with a molecule, collagen Q, to connect to the membrane of the neuromuscular junction. [[http://www.ncbi.nlm.nih.gov/pubmed/11804574]].  From the <scene name='Sandbox11/Original_structure/3'>overall tertiary structure</scene>, it can be seen that there are 17 alpha helices and 14 beta strands.  There  are 2 beta sheets formed from 3 anti-parallel and 11 anti-parallel beta sheets, respectively(maybe highlight with green scene).  


¤To do: Try to show 4 monomers, better alpha helices, explain polar/nonpolar regions, where binding site is
¤To do: Try to show 4 monomers, better alpha helices, explain polar/nonpolar regions, where binding site is