3qej: Difference between revisions

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[[Image:3qej.png|left|200px]]
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{{STRUCTURE_3qej|  PDB=3qej  |  SCENE=  }}  
{{STRUCTURE_3qej|  PDB=3qej  |  SCENE=  }}  
===S74E-dCK mutant in complex with UDP===
===S74E-dCK mutant in complex with UDP===
{{ABSTRACT_PUBMED_21351740}}


 
==Function==
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[[http://www.uniprot.org/uniprot/DCK_HUMAN DCK_HUMAN]] Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.<ref>PMID:18377927</ref> <ref>PMID:20614893</ref>
The line below this paragraph, {{ABSTRACT_PUBMED_21351740}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_21351740}}


==About this Structure==
==About this Structure==
[[3qej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QEJ OCA].  
[[3qej]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QEJ OCA].  
==See Also==
*[[Deoxycytidine kinase|Deoxycytidine kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:21351740</ref><references group="xtra"/>
<ref group="xtra">PMID:021351740</ref><references group="xtra"/><references/>
[[Category: Deoxycytidine kinase]]
[[Category: Deoxycytidine kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hazra, S.]]
[[Category: Hazra, S.]]
[[Category: Lavie, A.]]
[[Category: Lavie, A.]]
[[Category: Alpha/beta]]
[[Category: Atp binding]]
[[Category: Phosphoryl transfer]]
[[Category: Phosphorylation]]
[[Category: Transferase]]