3ril: Difference between revisions

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Authors: Orwig, S.D., Lieberman, R.L.
Authors: Orwig, S.D., Lieberman, R.L.


Description: THE ACID BETA-GLUCOSIDASE ACTIVE SITE EXHIBITS PLASTICITY IN BINDING 3,4,5,6-TETRAHYDROXYAZEPANE-BASED INHIBITORS: IMPLICATIONS FOR PHARMACOLOGICAL CHAPERONE DESIGN FOR GAUCHER DISEASE
Description: The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease