3ngx: Difference between revisions

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[[Image:3ngx.jpg|left|200px]]
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{{STRUCTURE_3ngx|  PDB=3ngx  |  SCENE=  }}  
{{STRUCTURE_3ngx|  PDB=3ngx  |  SCENE=  }}  
===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum===
===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum===
{{ABSTRACT_PUBMED_21333632}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/FOLD_THEAC FOLD_THEAC]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).
The line below this paragraph, {{ABSTRACT_PUBMED_21333632}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_21333632}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21333632</ref><references group="xtra"/>
<ref group="xtra">PMID:021333632</ref><references group="xtra"/><references/>
[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
[[Category: Hwang, K W.]]
[[Category: Hwang, K W.]]
[[Category: Lee, W H.]]
[[Category: Lee, W H.]]
[[Category: Sung, M W.]]
[[Category: Sung, M W.]]
[[Category: 10-methenyltetrahydrofolate]]
[[Category: 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate]]
[[Category: 10-methylenetetrahydrofolate to 5]]
[[Category: Catalyzes the oxidation of 5]]
[[Category: Hydrolase]]
[[Category: Methylenetetrahydrofolate dehydrogenase/cyclohydrolase]]
[[Category: Oxidoreductase]]
[[Category: The hydrolysis of 5]]

Revision as of 12:07, 24 April 2013

Template:STRUCTURE 3ngx

Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum

Template:ABSTRACT PUBMED 21333632

Function

[FOLD_THEAC] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).

About this Structure

3ngx is a 2 chain structure with sequence from Thermoplasma acidophilum. Full crystallographic information is available from OCA.

Reference

  1. Lee WH, Sung MW, Kim JH, Kim YK, Han A, Hwang KY. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011 Mar 18;406(3):459-63. Epub 2011 Feb 17. PMID:21333632 doi:10.1016/j.bbrc.2011.02.074

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