Ton: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 6: | Line 6: | ||
==Function== | ==Function== | ||
The Ton proteins are involved in the uptake of vitamin B12 and chelated-iron into the cell<ref>PMID: 17347522</ref>, and the system as a whole is known to be an energy-transducing system. Each of the three proteins involved have their separate role<ref name='Held'>PMID: 12193634</ref>. For more information, see the respective pages for TonB, ExbB and ExbD. | The Ton proteins are involved in the uptake of vitamin B12 and chelated-iron into the cell<ref>PMID: 17347522</ref>, and the system as a whole is known to be an energy-transducing system. Each of the three proteins involved have their separate role<ref name='Held'>PMID: 12193634</ref>. For more information, see the respective pages for TonB, ExbB and ExbD. | ||
The Ton system can be exploited by group B Colicins {see [[Colicin]] for more details) which include: | |||
*[[Colicin 5]] | |||
*[[Colicin 6]] | |||
*[[Colicin 7]] | |||
*[[Colicin 8]] | |||
*[[Colicin 9]] | |||
*[[Colicin 10]] | |||
*[[Colicin 1a]] | |||
*[[Colicin 1b]] | |||
*[[Colicin B]] | |||
*[[Colicin D]] | |||
*[[Colicin M]] | |||
*[[Colicin V]] | |||
*[[Colicin Js]] | |||
*[[Colicin Y]] | |||
==Interaction of Ton proteins== | ==Interaction of Ton proteins== | ||
| Line 11: | Line 27: | ||
# the transmembrane domain of TonB interacts with both ExbB and ExbD, which contribute to the stability of the protein and support the TonB-dependent active transport across the outer membrane. | # the transmembrane domain of TonB interacts with both ExbB and ExbD, which contribute to the stability of the protein and support the TonB-dependent active transport across the outer membrane. | ||
# ExbB and ExbD interact with each other, which has been suggested to play a part in the mechanism of energy transduction | # ExbB and ExbD interact with each other, which has been suggested to play a part in the mechanism of energy transduction | ||
== References== | == References== | ||
<references/> | <references/> | ||
