Homology modeling servers: Difference between revisions
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<font color="red">Caution:</font> | <font color="red">Caution:</font> | ||
Omitted in the sequence alignment, yet not indicated there by a gap. The 3D model lacks a spatial gap between the residues at the gap boundries, effectively ligating** them . This causes a shift in target-template registration, and produces a 3D model that fails to make apparent the absence of some residues in the template (unless the structural alignment is examined as the downloadable ''Project'' in [[DeepView]]). The absence of some residues will affect analyses of the 3D model, such as charge distribution, and distribution of [[evolutionary conservation]]. | Omitted in the sequence alignment, yet not indicated there by a gap. The 3D model lacks a spatial gap between the residues at the gap boundries, effectively ligating** them . This causes a shift in target-template registration, and produces a 3D model that fails to make apparent the absence of some residues in the template (unless the structural alignment is examined as the downloadable ''Project'' in [[DeepView]]). The absence of some residues will affect analyses of the 3D model, such as charge distribution, and distribution of [[Evolutionary Conservation|evolutionary conservation]]. | ||
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