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[[Image:3pix.png|left|200px]]
[[Image:3pix.png|left|200px]]


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{{STRUCTURE_3pix|  PDB=3pix  |  SCENE=  }}  
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===Crystal structure of BTK kinase domain complexed with 2-Isopropyl-7-(4-methyl-piperazin-1-yl)-4-(5-methyl-2H-pyrazol-3-ylamino)-2H-phthalazin-1-one===
===Crystal structure of BTK kinase domain complexed with 2-Isopropyl-7-(4-methyl-piperazin-1-yl)-4-(5-methyl-2H-pyrazol-3-ylamino)-2H-phthalazin-1-one===


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{{ABSTRACT_PUBMED_21280133}}


==About this Structure==
==About this Structure==
[[3pix]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIX OCA].  
[[3pix]] is a 1 chain structure of [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PIX OCA].  
 
==See Also==
*[[Tyrosine kinase|Tyrosine kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:21280133</ref><references group="xtra"/>
<ref group="xtra">PMID:021280133</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Kuglstatter, A.]]
[[Category: Kuglstatter, A.]]
[[Category: Wong, A.]]
[[Category: Wong, A.]]
[[Category: Dfg-in]]
[[Category: Helix c-out]]
[[Category: Transferase]]
[[Category: Transferase-inhibitor complex]]

Revision as of 04:08, 26 July 2012

File:3pix.png

Template:STRUCTURE 3pix

Crystal structure of BTK kinase domain complexed with 2-Isopropyl-7-(4-methyl-piperazin-1-yl)-4-(5-methyl-2H-pyrazol-3-ylamino)-2H-phthalazin-1-one

Template:ABSTRACT PUBMED 21280133

About this Structure

3pix is a 1 chain structure of Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Kuglstatter A, Wong A, Tsing S, Lee SW, Lou Y, Villasenor AG, Bradshaw JM, Shaw D, Barnett JW, Browner MF. Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures. Protein Sci. 2011 Feb;20(2):428-36. doi: 10.1002/pro.575. PMID:21280133 doi:10.1002/pro.575

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