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==Overview==

The plague-causing bacterium Yersinia pestis utilizes a contact-dependent, (type III) secretion system (T3SS) to transport virulence factors from the, bacterial cytosol directly into the interior of mammalian cells where they, interfere with signal transduction pathways that mediate phagocytosis and, the inflammatory response. The type III secretion apparatus is composed of, 20-25 different Yersinia secretion (Ysc) proteins. We report here the, structure of YscE, the smallest Ysc protein, which is a dimer in solution., The probable mode of oligomerization is discussed.

The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed.

==About this Structure==

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[[Category: Single protein]]

[[Category: Yersinia pestis]]

[[Category: Austin, B.P.]]

[[Category: Austin, B P.]]

[[Category: Phan, J.]]

[[Category: Waugh, D.S.]]

[[Category: Waugh, D S.]]

[[Category: chaperone]]

[[Category: export]]

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[[Category: yersinia]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:19:36 2008''

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@@ Line 4: / Line 4: @@
 ==Overview==
-The plague-causing bacterium Yersinia pestis utilizes a contact-dependent, (type III) secretion system (T3SS) to transport virulence factors from the, bacterial cytosol directly into the interior of mammalian cells where they, interfere with signal transduction pathways that mediate phagocytosis and, the inflammatory response. The type III secretion apparatus is composed of, 20-25 different Yersinia secretion (Ysc) proteins. We report here the, structure of YscE, the smallest Ysc protein, which is a dimer in solution., The probable mode of oligomerization is discussed.
+The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed.
 ==About this Structure==
@@ Line 13: / Line 13: @@
 [[Category: Single protein]]
 [[Category: Yersinia pestis]]
-[[Category: Austin, B.P.]]
+[[Category: Austin, B P.]]
 [[Category: Phan, J.]]
-[[Category: Waugh, D.S.]]
+[[Category: Waugh, D S.]]
 [[Category: chaperone]]
 [[Category: export]]
@@ Line 22: / Line 22: @@
 [[Category: yersinia]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:44:04 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:19:36 2008''