211d: Difference between revisions
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New page: left|200px<br /><applet load="211d" size="350" color="white" frame="true" align="right" spinBox="true" caption="211d, resolution 1.600Å" /> '''THE CRYSTAL AND MOL... |
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==Overview== | ==Overview== | ||
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was | The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures. | ||
==About this Structure== | ==About this Structure== | ||
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Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7492550 7492550] | Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7492550 7492550] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Arvantis, G | [[Category: Arvantis, G M.]] | ||
[[Category: Berman, H | [[Category: Berman, H M.]] | ||
[[Category: Gaffney, B.]] | [[Category: Gaffney, B.]] | ||
[[Category: Ginell, S | [[Category: Ginell, S L.]] | ||
[[Category: Jones, R.]] | [[Category: Jones, R.]] | ||
[[Category: Lessinger, L.]] | [[Category: Lessinger, L.]] | ||
[[Category: Parkinson, G | [[Category: Parkinson, G N.]] | ||
[[Category: PTN]] | [[Category: PTN]] | ||
[[Category: SPM]] | [[Category: SPM]] | ||
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[[Category: z-dna]] | [[Category: z-dna]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:58 2008'' | ||
