238d: Difference between revisions

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==Overview==

The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been, determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of, d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no, cobalt hexammine ions are bound to the DNA structure. This contrasts with, the recently determined crystal structure of d(AGGCATGCCT) which has a, similar DNA conformation and cobalt hexammine ions bound directly to the, DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of, the crystal packing of this sequence leads to an understanding of how, cobalt hexammine binding to DNA occurs and its role in determining DNA, conformation.

The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation.

==About this Structure==

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Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8877561 8877561]

[[Category: Protein complex]]

[[Category: Nunn, C.M.]]

[[Category: Nunn, C M.]]

[[Category: a-dna]]

[[Category: base triplet]]

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[[Category: flipped-out bases]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:21:33 2008''

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@@ Line 4: / Line 4: @@
 ==Overview==
-The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been, determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of, d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no, cobalt hexammine ions are bound to the DNA structure. This contrasts with, the recently determined crystal structure of d(AGGCATGCCT) which has a, similar DNA conformation and cobalt hexammine ions bound directly to the, DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of, the crystal packing of this sequence leads to an understanding of how, cobalt hexammine binding to DNA occurs and its role in determining DNA, conformation.
+The crystal structure of the DNA decamer d(AGGBrCATGCCT) has been determined to a resolution of 2.0 A and R factor of 19.6%. Crystals of d(AGGBrCATGCCT) were grown in the presence of cobalt hexammine but no cobalt hexammine ions are bound to the DNA structure. This contrasts with the recently determined crystal structure of d(AGGCATGCCT) which has a similar DNA conformation and cobalt hexammine ions bound directly to the DNA. Comparison with the structure of d(AGGCATGCCT) and appreciation of the crystal packing of this sequence leads to an understanding of how cobalt hexammine binding to DNA occurs and its role in determining DNA conformation.
 ==About this Structure==
@@ Line 12: / Line 12: @@
 Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA., Nunn CM, J Biomol Struct Dyn. 1996 Aug;14(1):49-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8877561 8877561]
 [[Category: Protein complex]]
-[[Category: Nunn, C.M.]]
+[[Category: Nunn, C M.]]
 [[Category: a-dna]]
 [[Category: base triplet]]
@@ Line 18: / Line 18: @@
 [[Category: flipped-out bases]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:48:33 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:21:33 2008''