281d: Difference between revisions

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==Overview==

The crystal structure of the self-complementary DNA octamer d(GGCATGCC), has been determined to a resolution of 2.38 A and R factor of 17.1%. The, structure is an A-DNA octamer duplex with Watson-Crick base pairing along, its length. This sequence extends the investigation of octamer duplexes of, the type d(GGX(4)CC) which assume P6(1) packing within the, crystallographic unit cell. The A-DNA duplex is non-linear with a helix, axis curvature of 7 degrees and bending towards the DNA minor groove. In, view of the biological importance of protein recognition of some A-DNA, sequences the minor-groove geometry and helix-axis curvature for this, structure is compared with all others of the type d(GGXATXCC).

The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).

==About this Structure==

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[[Category: Protein complex]]

[[Category: Neidle, S.]]

[[Category: Nunn, C.M.]]

[[Category: Nunn, C M.]]

[[Category: a-dna]]

[[Category: double helix]]

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@@ Line 4: / Line 4: @@
 ==Overview==
-The crystal structure of the self-complementary DNA octamer d(GGCATGCC), has been determined to a resolution of 2.38 A and R factor of 17.1%. The, structure is an A-DNA octamer duplex with Watson-Crick base pairing along, its length. This sequence extends the investigation of octamer duplexes of, the type d(GGX(4)CC) which assume P6(1) packing within the, crystallographic unit cell. The A-DNA duplex is non-linear with a helix, axis curvature of 7 degrees and bending towards the DNA minor groove. In, view of the biological importance of protein recognition of some A-DNA, sequences the minor-groove geometry and helix-axis curvature for this, structure is compared with all others of the type d(GGXATXCC).
+The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).
 ==About this Structure==
@@ Line 13: / Line 13: @@
 [[Category: Protein complex]]
 [[Category: Neidle, S.]]
-[[Category: Nunn, C.M.]]
+[[Category: Nunn, C M.]]
 [[Category: a-dna]]
 [[Category: double helix]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:50:30 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:22:10 2008''