3rnv: Difference between revisions
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{{STRUCTURE_3rnv| PDB=3rnv | SCENE= }} | {{STRUCTURE_3rnv| PDB=3rnv | SCENE= }} | ||
===Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase=== | ===Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/POLG_TUMVJ POLG_TUMVJ]] Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification. Nuclear inclusion protein B: a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity). Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity). Both 6K peptides are indispensable for virus replication (By similarity). Nuclear inclusion protein A: has RNA-binding and proteolytic activities. | |||
==About this Structure== | ==About this Structure== | ||
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[[Category: Turnip mosaic virus]] | [[Category: Turnip mosaic virus]] | ||
[[Category: Ye, K.]] | [[Category: Ye, K.]] | ||
[[Category: Cysteine protease]] | |||
[[Category: Hydrolase]] | |||
[[Category: Proteolysis]] | |||
Revision as of 07:45, 16 May 2013
Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase
Function
[POLG_TUMVJ] Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification. Nuclear inclusion protein B: a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity). Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity). Both 6K peptides are indispensable for virus replication (By similarity). Nuclear inclusion protein A: has RNA-binding and proteolytic activities.
About this Structure
3rnv is a 1 chain structure with sequence from Turnip mosaic virus. Full crystallographic information is available from OCA.
