2a5w: Difference between revisions

Line 4:

==Overview==

The X-ray structure of the gamma-subunit of the dissimilatory sulfite, reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and, 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the, latter being cocrystallized with the oxidizing agent tert-butyl, hydroperoxide. The fold corresponds to that of the homologous protein from, Pyrobaculum aerophilum but is significantly more compact. The most, interesting, highly conserved C-terminal arm adopts a well-defined, conformation in A. fulgidus DsrC in contrast to the completely disordered, conformation in P. aerophilum DsrC. The functional relevance of both, conformations and of a potentially redox-active disulfide bond between the, strictly invariant Cys103 and Cys114 are discussed.

The X-ray structure of the gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the latter being cocrystallized with the oxidizing agent tert-butyl hydroperoxide. The fold corresponds to that of the homologous protein from Pyrobaculum aerophilum but is significantly more compact. The most interesting, highly conserved C-terminal arm adopts a well-defined conformation in A. fulgidus DsrC in contrast to the completely disordered conformation in P. aerophilum DsrC. The functional relevance of both conformations and of a potentially redox-active disulfide bond between the strictly invariant Cys103 and Cys114 are discussed.

==About this Structure==

Line 16:

[[Category: Hedderich, R.]]

[[Category: Kahnt, J.]]

[[Category: Mander, G.J.]]

[[Category: Mander, G J.]]

[[Category: Warkentin, E.]]

[[Category: Weiss, M.S.]]

[[Category: Weiss, M S.]]

[[Category: SO4]]

[[Category: orthogonal helix bundle]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jan 29 17~~:55:06 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:54 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 4: / Line 4: @@
 ==Overview==
-The X-ray structure of the gamma-subunit of the dissimilatory sulfite, reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and, 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the, latter being cocrystallized with the oxidizing agent tert-butyl, hydroperoxide. The fold corresponds to that of the homologous protein from, Pyrobaculum aerophilum but is significantly more compact. The most, interesting, highly conserved C-terminal arm adopts a well-defined, conformation in A. fulgidus DsrC in contrast to the completely disordered, conformation in P. aerophilum DsrC. The functional relevance of both, conformations and of a potentially redox-active disulfide bond between the, strictly invariant Cys103 and Cys114 are discussed.
+The X-ray structure of the gamma-subunit of the dissimilatory sulfite reductase (DsrC) from Archaeoglobus fulgidus was determined at 1.12 and 2.1A resolution, in the two crystal forms named DsrC(nat) and DsrC(ox) the latter being cocrystallized with the oxidizing agent tert-butyl hydroperoxide. The fold corresponds to that of the homologous protein from Pyrobaculum aerophilum but is significantly more compact. The most interesting, highly conserved C-terminal arm adopts a well-defined conformation in A. fulgidus DsrC in contrast to the completely disordered conformation in P. aerophilum DsrC. The functional relevance of both conformations and of a potentially redox-active disulfide bond between the strictly invariant Cys103 and Cys114 are discussed.
 ==About this Structure==
@@ Line 16: / Line 16: @@
 [[Category: Hedderich, R.]]
 [[Category: Kahnt, J.]]
-[[Category: Mander, G.J.]]
+[[Category: Mander, G J.]]
 [[Category: Warkentin, E.]]
-[[Category: Weiss, M.S.]]
+[[Category: Weiss, M S.]]
 [[Category: SO4]]
 [[Category: orthogonal helix bundle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:55:06 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:54 2008''