2x04: Difference between revisions

Revision as of 10:55, 13 March 2013

2x04 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Jinek M, Fabian MR, Coyle SM, Sonenberg N, Doudna JA. Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation. Nat Struct Mol Biol. 2010 Feb;17(2):238-40. Epub 2010 Jan 24. PMID:20098421 doi:10.1038/nsmb.1768
Tritschler F, Huntzinger E, Izaurralde E. Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of deja vu. Nat Rev Mol Cell Biol. 2010 May;11(5):379-84. Epub 2010 Apr 9. PMID:20379206 doi:10.1038/nrm2885

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-[[Image:2x04.png|left|200px]]
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 {{STRUCTURE_2x04|  PDB=2x04  |  SCENE=  }}
 ===CRYSTAL STRUCTURE OF THE PABC-TNRC6C COMPLEX===
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 [[Category: Jinek, M.]]
 [[Category: Sonenberg, N.]]
+[[Category: Deadenylation]]
+[[Category: Methylation]]
+[[Category: Microrna silencing]]
+[[Category: Mrna processing]]
+[[Category: Mrna splicing]]
+[[Category: Nucleus]]
+[[Category: Peptide-rna binding protein complex]]
+[[Category: Phosphoprotein]]
+[[Category: Protein-protein complex]]
+[[Category: Rna-mediated gene silencing]]
+[[Category: Spliceosome]]
+[[Category: Translation regulation]]