User:Wayne Decatur/kink-turn motif: Difference between revisions

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{{Button Toggle NucleicDrumsColorScheme}} {{ColorKey Bases RNA}}
{{Button Toggle NucleicDrumsColorScheme}} {{ColorKey Bases RNA}}
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[[kink-turn motif|The kink-turn motif]] is a common RNA structural motif that consists of helix–internal loop–helix motif that introduces a very tight kink into the helical axis, as illustrated in the 3D structure window the left. Originally identified in the course of analyzing the [[Large Ribosomal Subunit of Haloarcula|large ribosomal subunit]]<ref name="kleinref">PMID: 11483524</ref>, this RNA structural motif was also identified in other RNAs. Particular instances have been called the GA motif <ref>PMID: 11497434</ref>.
[[kink-turn motif|The kink-turn motif]] is a common RNA structural motif that consists of helix–internal loop–helix motif that introduces a very tight kink into the helical axis, as illustrated in the figure below and 3D structure window on the right. Originally identified in the course of analyzing the [[Large Ribosomal Subunit of Haloarcula|large ribosomal subunit]]<ref name="kleinref">PMID: 11483524</ref>, this RNA structural motif was also identified in other RNAs. Particular instances have been called the GA motif <ref>PMID: 11497434</ref>.
 
[[Image:Kink-turn.png|center|419px]]<br>
 
The kink-turn motif includes the [[A-minor motif]].
The kink-turn motif includes the [[A-minor motif]].
Many kink-turns bind proteins; however, that trait is not universal. They can mediate RNA tertiary structure interactions as well.
Many kink-turns bind proteins; however, that trait is not universal. They can mediate RNA tertiary structure interactions as well.
[[Image:Kink-turn.png|center|189px]]<br>


An excellent introduction can be found [http://www.dundee.ac.uk/biocentre/nasg/kturn/index.php here as part of a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase">PMID: 20562215</ref>.
An excellent introduction can be found [http://www.dundee.ac.uk/biocentre/nasg/kturn/index.php here as part of a structural database for k-turn motifs in RNA by the Lilley group]<ref name="lilleydatabase">PMID: 20562215</ref>.
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