Colicin Immunity Protein: Difference between revisions
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[[Image: | [[Image:1ayi.png|left|200px|thumb|Crystal Structure of Colicin immunity protein, [[1ayi]]]] | ||
{{ | {{STRUCTURE_1ayi| PDB=1ayi | SIZE=300| SCENE= |right|CAPTION=Colicin-E7 immunity protein, [[1ayi]] }} | ||
Immunity proteins against [[Colicin]]s (EcCIP) are produced by ''E. coli'' alongside the relevant colicin protein (EcCol) to protect the cell from the cytotoxic domain of the colicin. Usually this involves binding to and blocking the active site of the domain, to prevent it from targeting the cells own mechanisms. | Immunity proteins against [[Colicin]]s (EcCIP) are produced by ''E. coli'' alongside the relevant colicin protein (EcCol) to protect the cell from the cytotoxic domain of the colicin. Usually this involves binding to and blocking the active site of the domain, to prevent it from targeting the cells own mechanisms. | ||
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===Colicin-E7 immunity protein=== | ===Colicin-E7 immunity protein=== | ||
[[1ayi]], [[1unk]], [[1cei]] – EcCIPE7<BR /> | |||
[[2k0d]] - EcCIPE7 - NMR<br /> | |||
[[1mz8]], [[7cei]] – EcCIPE7 + EcColE7 nuclease domain<br /> | [[1mz8]], [[7cei]] – EcCIPE7 + EcColE7 nuclease domain<br /> | ||
[[2jaz]], [[2jb0]], [[2jbg]], [[1znv]] – EcCIPE7 + EcColE7 nuclease domain (mutant) <BR /> | [[2jaz]], [[2jb0]], [[2jbg]], [[1znv]] – EcCIPE7 + EcColE7 nuclease domain (mutant) <BR /> | ||
