3mg8: Difference between revisions

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Revision as of 05:31, 18 May 2011

File:3mg8.jpg

Template:STRUCTURE 3mg8

Structure of yeast 20S open-gate proteasome with Compound 16

Template:ABSTRACT PUBMED 20632995

About this Structure

3mg8 is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. Blackburn C, Gigstad KM, Hales P, Garcia K, Jones M, Bruzzese FJ, Barrett C, Liu JX, Soucy TA, Sappal DS, Bump N, Olhava EJ, Fleming P, Dick LR, Tsu C, Sintchak MD, Blank JL. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem J. 2010 Aug 27;430(3):461-76. PMID:20632995 doi:10.1042/BJ20100383

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