2xqf: Difference between revisions

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[[Image:2xqf.png|left|200px]]
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{{STRUCTURE_2xqf|  PDB=2xqf  |  SCENE=  }}  
{{STRUCTURE_2xqf|  PDB=2xqf  |  SCENE=  }}  
===X-RAY STRUCTURE OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY RACEMIC VX===
===X-RAY STRUCTURE OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY RACEMIC VX===
{{ABSTRACT_PUBMED_21454498}}


==Disease==
[[http://www.uniprot.org/uniprot/CHLE_HUMAN CHLE_HUMAN]] Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:[http://omim.org/entry/177400 177400]]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_21454498}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/CHLE_HUMAN CHLE_HUMAN]] Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.<ref>PMID:19542320</ref><ref>PMID:19452557</ref>  
(as it appears on PubMed at http://www.pubmed.gov), where 21454498 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21454498}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:021454498</ref><references group="xtra"/>
<ref group="xtra">PMID:021454498</ref><references group="xtra"/><references/>
[[Category: Cholinesterase]]
[[Category: Cholinesterase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Noort, D.]]
[[Category: Noort, D.]]
[[Category: Wandhammer, M.]]
[[Category: Wandhammer, M.]]
[[Category: Bioscavenger]]
[[Category: Hydrolase]]
[[Category: Nerve agent]]
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