3q0h: Difference between revisions

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[[Image:3q0h.png|left|200px]]
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{{STRUCTURE_3q0h|  PDB=3q0h  |  SCENE=  }}  
{{STRUCTURE_3q0h|  PDB=3q0h  |  SCENE=  }}  
===Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)===
===Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)===


==Function==
[[http://www.uniprot.org/uniprot/TIGIT_HUMAN TIGIT_HUMAN]] Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.


==About this Structure==
==About this Structure==
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[[Category: Ramagopal, U A.]]
[[Category: Ramagopal, U A.]]
[[Category: Samanta, D.]]
[[Category: Samanta, D.]]
[[Category: Adhesion]]
[[Category: Immune receptor]]
[[Category: Immune system]]
[[Category: New york structural genomics research consortium]]
[[Category: Nysgrc]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
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