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Replication Terminator Protein (RTP) is a protein found in ''Bacillus Subtilis''(''B.Subtilis'') that plays an important role in the termination of bacterial chromosome replication. RTP binds to the circular bacterial genome to block the progression of DNA polymerase in a polar manner. A homologue of RTP have been found in ''Eschericia coli'' (''E.coli''), named “Termination Utilisation Substance” (Tus)
Replication Terminator Protein (RTP) is a protein found in ''Bacillus Subtilis''(''B.Subtilis'') that plays an important role in the termination of bacterial chromosome replication. RTP binds to the circular bacterial genome to block the progression of DNA polymerase in a polar manner. A homologue of RTP has been found in ''Eschericia coli'' (''E.coli''), named “Termination Utilisation Substance” (Tus)
[[Image:bsubtilisrtpschematic.png|300px|right|thumb| Schematic diagram of the ''B.subtilis'' genome showing clockwise and anticlockwise replication forks and traps. RTP is represented by the red and blue blocks.]]
[[Image:bsubtilisrtpschematic.png|300px|right|thumb| Schematic diagram of the ''B.subtilis'' genome showing clockwise and anticlockwise replication forks and traps. RTP is represented by the red and blue blocks.]]
==Introduction==
==Introduction==