User:Cameron Ball/Sandbox 1: Difference between revisions
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| Basic Cleft in Tus contacts major groove of DNA <ref> Kaplan, D.L and Bastia, D, Mechanisms of polar arrest of a replication fork, Molecular Microbiology 2009:72:2), pp 279-285 </ref> | | Basic Cleft in Tus contacts major groove of DNA <ref> Kaplan, D.L and Bastia, D, Mechanisms of polar arrest of a replication fork, Molecular Microbiology 2009:72:2), pp 279-285 </ref> | ||
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| ''Mechanism of Action'' | | '''Mechanism of Action''' | ||
| Binds to ''Ter'' site directionally, bends DNA and may contact DnaB protein directly to inhibit DNA melting | | Binds to ''Ter'' site directionally, bends DNA and may contact DnaB protein directly to inhibit DNA melting | ||
| Contacts DnaB to halt it's translocation along DNA <ref> Kaplan, D.L and Bastia, D, Mechanisms of polar arrest of a replication fork, Molecular Microbiology 2009:72:2), pp 279-285 </ref> | | Contacts DnaB to halt it's translocation along DNA <ref> Kaplan, D.L and Bastia, D, Mechanisms of polar arrest of a replication fork, Molecular Microbiology 2009:72:2), pp 279-285 </ref> | ||