3s2o: Difference between revisions
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===Fragment based discovery and optimisation of bace-1 inhibitors=== | |||
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{{ABSTRACT_PUBMED_20656487}} | |||
==About this Structure== | |||
[[3s2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:020656487</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Memapsin 2]] | |||
[[Category: Barker, J.]] | |||
[[Category: Godemann, R.]] | |||
[[Category: Hallett, D.]] | |||
[[Category: Kraemer, J.]] | |||
[[Category: Madden, J.]] | |||
[[Category: Smith, M A.]] | |||
Revision as of 05:39, 1 June 2011
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089