3pz2: Difference between revisions

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~~[[Image:3pz2.png|left|200px]]~~

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===Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP===

===~~Crystal structure~~ of ~~RabGGTase~~(~~DELTA LRR; DELTA IG~~) ~~in Complex with BMS3~~ and ~~lipid substrate GGPP===~~

==Disease==

[[http://www.uniprot.org/uniprot/PGTA_MOUSE PGTA_MOUSE]] Note=Defects in Rabggta are the cause of the gunmetal (gm) phenotype. Mice homozygous for gm have prolonged bleeding, thrombocytopenia and reduced platelet alpha- and delta-granule contents.

==Function==

[[http://www.uniprot.org/uniprot/PGTA_MOUSE PGTA_MOUSE]] Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively (By similarity).

==About this Structure==

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==Reference==

[[Category: Mus musculus]]

[[Category: Protein geranylgeranyltransferase type II]]

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[[Category: Stigter, E A.]]

[[Category: Waldmann, H.]]

[[Category: Chimera protein]]

[[Category: Fusion protein]]

[[Category: Protein prenylation]]

[[Category: Transferase-transferase inhibitor complex]]

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-[[Image:3pz2.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3pz2", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3pz2|  PDB=3pz2  |  SCENE=  }}
+===Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP===
-===Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP===
+==Disease==
+[[http://www.uniprot.org/uniprot/PGTA_MOUSE PGTA_MOUSE]] Note=Defects in Rabggta are the cause of the gunmetal (gm) phenotype. Mice homozygous for gm have prolonged bleeding, thrombocytopenia and reduced platelet alpha- and delta-granule contents.
+==Function==
+[[http://www.uniprot.org/uniprot/PGTA_MOUSE PGTA_MOUSE]] Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively (By similarity).
 ==About this Structure==
@@ Line 16: / Line 12: @@
 ==Reference==
-<ref group="xtra">PMID:021520375</ref><references group="xtra"/>
+<ref group="xtra">PMID:021520375</ref><references group="xtra"/><references/>
 [[Category: Mus musculus]]
 [[Category: Protein geranylgeranyltransferase type II]]
@@ Line 26: / Line 22: @@
 [[Category: Stigter, E A.]]
 [[Category: Waldmann, H.]]
+[[Category: Chimera protein]]
+[[Category: Fusion protein]]
+[[Category: Protein prenylation]]
+[[Category: Transferase-transferase inhibitor complex]]