3h6v: Difference between revisions

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[[Image:3h6v.png|left|200px]]
[[Image:3h6v.png|left|200px]]


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===Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution===
===Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution===


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{{ABSTRACT_PUBMED_19591837}}


==About this Structure==
==About this Structure==
[[3h6v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6V OCA].  
[[3h6v]] is a 2 chain structure of [[Ionotropic Glutamate Receptors]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6V OCA].  
 
==See Also==
*[[Ionotropic Glutamate Receptors|Ionotropic Glutamate Receptors]]


==Reference==
==Reference==

Revision as of 07:35, 27 July 2012

File:3h6v.png

Template:STRUCTURE 3h6v

Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5206 at 2.10 A resolution

Template:ABSTRACT PUBMED 19591837

About this Structure

3h6v is a 2 chain structure of Ionotropic Glutamate Receptors with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hald H, Ahring PK, Timmermann DB, Liljefors T, Gajhede M, Kastrup JS. Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J Mol Biol. 2009 Sep 4;391(5):906-17. Epub 2009 Jul 8. PMID:19591837 doi:10.1016/j.jmb.2009.07.002
  2. Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
  3. Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 2002 May 16;417(6886):245-53. PMID:12015593 doi:10.1038/417245a

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