3ff9: Difference between revisions

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[[Image:3ff9.png|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3ff9", creates the "Structure Box" on the page.
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{{STRUCTURE_3ff9|  PDB=3ff9  |  SCENE=  }}  
{{STRUCTURE_3ff9|  PDB=3ff9  |  SCENE=  }}  
===Structure of NK cell receptor KLRG1===
===Structure of NK cell receptor KLRG1===
{{ABSTRACT_PUBMED_19604491}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/KLRG1_MOUSE KLRG1_MOUSE]] Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.<ref>PMID:19604491</ref>  
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{{ABSTRACT_PUBMED_19604491}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:019604491</ref><references group="xtra"/>
<ref group="xtra">PMID:019604491</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Li, Y.]]
[[Category: Li, Y.]]

Revision as of 09:11, 27 March 2013

Template:STRUCTURE 3ff9

Structure of NK cell receptor KLRG1

Template:ABSTRACT PUBMED 19604491

Function

[KLRG1_MOUSE] Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.[1]

About this Structure

3ff9 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Li Y, Hofmann M, Wang Q, Teng L, Chlewicki LK, Pircher H, Mariuzza RA. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity. 2009 Jul 17;31(1):35-46. PMID:19604491 doi:S1074-7613(09)00276-3
  1. ↑ Li Y, Hofmann M, Wang Q, Teng L, Chlewicki LK, Pircher H, Mariuzza RA. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity. 2009 Jul 17;31(1):35-46. PMID:19604491 doi:S1074-7613(09)00276-3

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