2bky: Difference between revisions
m Protected "2bky" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2bky| PDB=2bky | SCENE= }} | {{STRUCTURE_2bky| PDB=2bky | SCENE= }} | ||
===CRYSTAL STRUCTURE OF THE ALBA1:ALBA2 HETERODIMER FROM SULFOLOBUS SOLFATARICUS=== | ===CRYSTAL STRUCTURE OF THE ALBA1:ALBA2 HETERODIMER FROM SULFOLOBUS SOLFATARICUS=== | ||
{{ABSTRACT_PUBMED_16004869}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ALBA1_SULSO ALBA1_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.[HAMAP-Rule:MF_01122] [[http://www.uniprot.org/uniprot/ALBA2_SULSO ALBA2_SULSO]] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
| Line 22: | Line 10: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016004869</ref><references group="xtra"/> | <ref group="xtra">PMID:016004869</ref><references group="xtra"/><references/> | ||
[[Category: Sulfolobus solfataricus]] | [[Category: Sulfolobus solfataricus]] | ||
[[Category: Bullough, P A.]] | [[Category: Bullough, P A.]] | ||
| Line 31: | Line 19: | ||
[[Category: Waltho, J P.]] | [[Category: Waltho, J P.]] | ||
[[Category: White, M F.]] | [[Category: White, M F.]] | ||
[[Category: Archaeal dna binding protein]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Dna condensation]] | |||
[[Category: Dna-binding]] | |||
[[Category: Rna-binding]] | |||
Revision as of 02:06, 4 April 2013
CRYSTAL STRUCTURE OF THE ALBA1:ALBA2 HETERODIMER FROM SULFOLOBUS SOLFATARICUS
Template:ABSTRACT PUBMED 16004869
Function
[ALBA1_SULSO] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. May be involved in DNA compaction. May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.[HAMAP-Rule:MF_01122] [ALBA2_SULSO] Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
About this Structure
2bky is a 4 chain structure with sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.
Reference
- Jelinska C, Conroy MJ, Craven CJ, Hounslow AM, Bullough PA, Waltho JP, Taylor GL, White MF. Obligate heterodimerization of the archaeal Alba2 protein with Alba1 provides a mechanism for control of DNA packaging. Structure. 2005 Jul;13(7):963-71. PMID:16004869 doi:10.1016/j.str.2005.04.016
