3ntz: Difference between revisions
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[[Image:3ntz.png|left|200px]] | [[Image:3ntz.png|left|200px]] | ||
{{STRUCTURE_3ntz| PDB=3ntz | SCENE= }} | {{STRUCTURE_3ntz| PDB=3ntz | SCENE= }} | ||
===Design, Synthesis, Biological Evaluation and X-ray Crystal Structures of Novel Classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors=== | ===Design, Synthesis, Biological Evaluation and X-ray Crystal Structures of Novel Classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors=== | ||
{{ABSTRACT_PUBMED_21550809}} | {{ABSTRACT_PUBMED_21550809}} | ||
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==See Also== | ==See Also== | ||
*[[Dihydrofolate reductase]] | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | ||
==Reference== | ==Reference== | ||
Revision as of 06:45, 27 July 2012
Design, Synthesis, Biological Evaluation and X-ray Crystal Structures of Novel Classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors
Template:ABSTRACT PUBMED 21550809
About this Structure
3ntz is a 1 chain structure of Dihydrofolate reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhang X, Zhou X, Kisliuk RL, Piraino J, Cody V, Gangjee A. Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors. Bioorg Med Chem. 2011 Apr 9. PMID:21550809 doi:10.1016/j.bmc.2011.03.067
