3s7a: Difference between revisions
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[[Image:3s7a.jpg|left|200px]] | |||
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{{STRUCTURE_3s7a| PDB=3s7a | SCENE= }} | |||
===Human dihydrofolate reductase binary complex with PT684=== | |||
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{{ABSTRACT_PUBMED_21931219}} | |||
==About this Structure== | |||
[[3s7a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S7A OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021931219</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Cody, V.]] | |||
[[Category: Nowak, J.]] | |||
[[Category: Pace, J.]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
[[Category: Reductase]] | |||
[[Category: Single polypeptide chain]] | |||
Revision as of 06:40, 5 October 2011
Human dihydrofolate reductase binary complex with PT684
Template:ABSTRACT PUBMED 21931219
About this Structure
3s7a is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cody V, Pace J, Nowak J. Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpter idine reveals an unusual binding mode. Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):875-80. Epub 2011, Sep 8. PMID:21931219 doi:10.1107/S0907444911030071