2i22: Difference between revisions

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[[Image:2i22.png|left|200px]]
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{{STRUCTURE_2i22|  PDB=2i22  |  SCENE=  }}  
{{STRUCTURE_2i22|  PDB=2i22  |  SCENE=  }}  
===Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate===
===Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate===
{{ABSTRACT_PUBMED_18056714}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/GMHA_ECOLI GMHA_ECOLI]] Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.<ref>PMID:11751812</ref> <ref>PMID:18056714</ref> 
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{{ABSTRACT_PUBMED_18056714}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:018056714</ref><references group="xtra"/>
<ref group="xtra">PMID:018056714</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Blakely, K.]]
[[Category: Blakely, K.]]

Revision as of 12:07, 24 April 2013

Template:STRUCTURE 2i22

Crystal structure of Escherichia coli phosphoheptose isomerase in complex with reaction substrate sedoheptulose 7-phosphate

Template:ABSTRACT PUBMED 18056714

Function

[GMHA_ECOLI] Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.[1] [2]

About this Structure

2i22 is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Taylor PL, Blakely KM, de Leon GP, Walker JR, McArthur F, Evdokimova E, Zhang K, Valvano MA, Wright GD, Junop MS. Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. J Biol Chem. 2008 Feb 1;283(5):2835-45. Epub 2007 Dec 3. PMID:18056714 doi:10.1074/jbc.M706163200
  1. ↑ Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P. Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli. J Bacteriol. 2002 Jan;184(2):363-9. PMID:11751812
  2. ↑ Taylor PL, Blakely KM, de Leon GP, Walker JR, McArthur F, Evdokimova E, Zhang K, Valvano MA, Wright GD, Junop MS. Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants. J Biol Chem. 2008 Feb 1;283(5):2835-45. Epub 2007 Dec 3. PMID:18056714 doi:10.1074/jbc.M706163200

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