2y43: Difference between revisions
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{{STRUCTURE_2y43| PDB=2y43 | SCENE= }} | {{STRUCTURE_2y43| PDB=2y43 | SCENE= }} | ||
===RAD18 UBIQUITIN LIGASE RING DOMAIN STRUCTURE=== | ===RAD18 UBIQUITIN LIGASE RING DOMAIN STRUCTURE=== | ||
{{ABSTRACT_PUBMED_21549715}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RAD18_HUMAN RAD18_HUMAN]] E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.<ref>PMID:17108083</ref> <ref>PMID:21659603</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021549715</ref><references group="xtra"/> | <ref group="xtra">PMID:021549715</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hibbert, R G.]] | [[Category: Hibbert, R G.]] | ||