Sandbox 121: Difference between revisions
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==='''Background Information'''=== | ==='''Background Information'''=== | ||
[[Image:B2AR-Adernergic synapse.JPG|thumb|alt= Alt text| Adernergic Synapse | [[Image:B2AR-Adernergic synapse.JPG|thumb|alt= Alt text| Adernergic Synapse |350px]] | ||
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NE binds to adrenergic receptors embedded in the postsynaptic effector cell membrane. | NE binds to adrenergic receptors embedded in the postsynaptic effector cell membrane. | ||
Following binding of NE, to either alpha or beta receptors, conformational changes in the receptor lead to a disassociation of the G protein from the cytoplasmic face of the receptor which activates a second messenger, initiating a signaling cascade. | Following binding of NE, to either alpha or beta receptors, conformational changes in the receptor lead to a disassociation of the G protein from the cytoplasmic face of the receptor which activates a second messenger, initiating a signaling cascade. | ||
[[Image:B2AR-Norepinephrine.JPG|thumb|alt= Alt text| Norephrine|250px]] | |||
{{clear}} | {{clear}} | ||