Sandbox 121: Difference between revisions

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==='''Background Information'''===
==='''Background Information'''===
[[Image:B2AR-Adernergic synapse.JPG|thumb|alt= Alt text| Adernergic Synapse |350px] [Image:B2AR-Norepinephrine.JPG|thumb|alt= Alt text| Norephrine|350px]]
[[Image:B2AR-Adernergic synapse.JPG|thumb|alt= Alt text| Adernergic Synapse |350px]]  




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NE binds to adrenergic receptors embedded in the postsynaptic effector cell membrane.
NE binds to adrenergic receptors embedded in the postsynaptic effector cell membrane.
Following binding of NE, to either alpha or beta receptors,  conformational changes in the receptor lead to a disassociation of the G protein from the cytoplasmic face of the receptor which activates a second messenger, initiating a signaling cascade.
Following binding of NE, to either alpha or beta receptors,  conformational changes in the receptor lead to a disassociation of the G protein from the cytoplasmic face of the receptor which activates a second messenger, initiating a signaling cascade.
[[Image:B2AR-Norepinephrine.JPG|thumb|alt= Alt text| Norephrine|250px]]


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