2lez: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2lez|  PDB=2lez  |  SCENE=  }}
===Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a===


The entry 2lez is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref> 


Authors: Lemak, A., Yee, A., Houliston, S., Garcia, M., Daniels, C., Savchenko, A., Arrowsmith, C., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
==About this Structure==
[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA].  


Description: Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a
==Reference==
<references group="xtra"/><references/>
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Category: Arrowsmith, C.]]
[[Category: Daniels, C.]]
[[Category: Garcia, M.]]
[[Category: Houliston, S.]]
[[Category: Lemak, A.]]
[[Category: Montelione, G T.]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Savchenko, A.]]
[[Category: Yee, A.]]
[[Category: Bacterial effector]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]
[[Category: Virulence factor]]
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