1tq3: Difference between revisions

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~~[[Image:1tq3.png|left|200px]]~~

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===Higher resolution crystal structure of the third PDZ domain of post synaptic PSD-95 protein===

==Function==

[[http://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref>

==About this Structure==

[[1tq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ3 OCA].

==Reference==

[[Category: Rattus norvegicus]]

[[Category: Kovari, L.]]

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-[[Image:1tq3.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_1tq3", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_1tq3|  PDB=1tq3  |  SCENE=  }}
 ===Higher resolution crystal structure of the third PDZ domain of post synaptic PSD-95 protein===
+==Function==
+[[http://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref>
 ==About this Structure==
 [[1tq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQ3 OCA].
+==Reference==
+<references group="xtra"/><references/>
 [[Category: Rattus norvegicus]]
 [[Category: Kovari, L.]]