Caspase: Difference between revisions

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==3D structures of caspase==
==3D structures of caspase==
''Update November 2011''


===CASP-1===
===CASP-1===
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[[1sc3]] - hCASP (mutant) + malonate<br />
[[1sc3]] - hCASP (mutant) + malonate<br />
[[3d6f]], [[3d6h]], [[3d6m]], [[1ibc]] - hCASP (mutant) + polypeptide inhibitor<br />
[[3d6f]], [[3d6h]], [[3d6m]], [[1ibc]] - hCASP (mutant) + polypeptide inhibitor<br />
[[2hbq]], [[1bmq]] - hCASP + inhibitor<br />
[[2hbq]], [[1bmq]], [[3ns7]] - hCASP + inhibitor<br />
[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br />
[[2h4w]], [[2h4y]], [[2h51]], [[2h54]], [[2hbr]], [[2hby]], [[2hbz]], [[2h48]], [[2fqq]], [[1rwk]], [[1rwm]], [[1rwn]], [[1rwo]], [[1rwp]], [[1rwv]], [[1rww]], [[1rwx]] - hCASP (mutant) + inhibitor<br />
[[1m72]] – SfCASP + polypeptide inhibitor<br />
[[1m72]] – SfCASP + polypeptide inhibitor<br />
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[[2p2c]] – hCASP<br />
[[2p2c]] – hCASP<br />
[[1pyo]] - hCASP + polypeptide inhibitor<br />
[[3r7s]] - hCASP subunits P12, P18<br />
[[1pyo]], [[3r5j]], [[3r6g]], [[3r6l]], [[3r7b]], [[3r7n]], [[3rjm]] - hCASP + polypeptide inhibitor<br />


===CASP-3===
===CASP-3===


[[1qx3]] - hCASP<br />  
[[1qx3]] - hCASP<br />
[[2xyg]], [[2xyh]], [[2xyp]] – hCASP subunits P12, P17 + inhibitor<brt />
[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[[[2h65]], [[1cp3]], [[1pau]] – hCASP + polypeptide inhibitor<br />
[[3pcx]], [[3pd1]], [[3pd0]], [[3gjq]], [[3gjr]], [[3gjs]], [[3gjt]], [[3edq]], [[3edr]], [[2cnk]], [[2cnl]], [[2cnn]], [[2cno]], [[2cdr]], [[[[2h65]], [[1cp3]], [[1pau]] – hCASP + polypeptide inhibitor<br />
[[2dko]], [[2cjx]], [[2cjy]] - hCASP (mutant) + polypeptide inhibitor<br />
[[2dko]], [[2cjx]], [[2cjy]] - hCASP (mutant) + polypeptide inhibitor<br />
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[[3p45]], [[3k7e]], [[2wdp]] – hCASP<br />
[[3p45]], [[3k7e]], [[2wdp]] – hCASP<br />
[[3nkf]], [[3nr2]] – hCASP (mutant) <br />
[[3nkf]], [[3nr2]] – hCASP (mutant) <br />
[[3od5]] – hCASP + polypeptide inhibitor<br />
[[3od5]], [[3p4u]], [[3qnw]] – hCASP + polypeptide inhibitor<br />


===CASP-7===
===CASP-7===


[[3rk5]], [[3ibf]] – hCASP<br />  
[[3rk5]], [[3ibf]] – hCASP<br />  
[[1k86]] - hCASP (mutant) <br />
[[1k86]], [[3r5k]] - hCASP (mutant) <br />
[[1k88]] – hpro-CASP (mutant) <br />
[[1k88]] – hpro-CASP (mutant) <br />
[[3ibc]], [[2ql5]], [[2ql7]], [[2ql9]], [[2qlb]], [[2qlf]], [[2qlj]], [[1f1j]] - hCASP + polypeptide inhibitor<br />
[[3ibc]], [[2ql5]], [[2ql7]], [[2ql9]], [[2qlb]], [[2qlf]], [[2qlj]], [[1f1j]] - hCASP + polypeptide inhibitor<br />
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[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br />
[[1nw9]] – hCASP catalytic domain + XIAP-BIR3<br />
[[3ygs]] – hpro-CASP + APAF-1 CARD
[[3ygs]] – hpro-CASP + APAF-1 CARD
[[2fp3]] – DmCASP NC – ''Drosophila melanogaster''<br />
[[3sip]] – DmCASP + apoptosis inhibitor<br />