1s7p: Difference between revisions

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~~[[Image:1s7p.png|left|200px]]~~

~~<!--~~

~~The line below this paragraph, containing "STRUCTURE_1s7p", creates the "Structure Box" on the page.~~

~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~

~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~

~~or leave the SCENE parameter empty for the default display.~~

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===Solution structure of thermolysin digested microcin J25===

==Function==

~~<!--~~

[[http://www.uniprot.org/uniprot/MCJA_ECOLI MCJA_ECOLI]] Peptide antibiotic that functions through inhibition of the bacterial DNA-dependent RNA polymerase (RNAP). May inhibit transcription by binding in RNAP secondary channel and blocking nucleotide substrates access to the catalytic center. Exhibits potent bacteriocidal activity against a range of Enterobacteriaceae, including several pathogenic E.coli, Salmonella and Shigella strains. Also acts on the cytoplasmic membrane of Salmonella newport, producing alteration of membrane permeability and disruption of the subsequent gradient dissipation, which inhibits several processes essential for cell viability, such as oxygen consumption. Induces bacterial filamentation in susceptible cells in a non-SOS-dependent way, but this phenotype may result from impaired transcription of genes coding for cell division proteins.<ref>PMID:11731133</ref> <ref>PMID:11443089</ref> <ref>PMID:12401787</ref>

~~The line below this paragraph, {{ABSTRACT_PUBMED_15096038}}, adds the Publication Abstract to the page~~

~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~), ~~where 15096038 is~~ the ~~PubMed ID number~~.

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~~{{ABSTRACT_PUBMED_15096038}}~~

==About this Structure==

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==Reference==

[[Category: Escherichia coli]]

[[Category: Afonso, C.]]

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@@ Line 1: / Line 1: @@
-[[Image:1s7p.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_1s7p", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_1s7p|  PDB=1s7p  |  SCENE=  }}
 ===Solution structure of thermolysin digested microcin J25===
+{{ABSTRACT_PUBMED_15096038}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/MCJA_ECOLI MCJA_ECOLI]] Peptide antibiotic that functions through inhibition of the bacterial DNA-dependent RNA polymerase (RNAP). May inhibit transcription by binding in RNAP secondary channel and blocking nucleotide substrates access to the catalytic center. Exhibits potent bacteriocidal activity against a range of Enterobacteriaceae, including several pathogenic E.coli, Salmonella and Shigella strains. Also acts on the cytoplasmic membrane of Salmonella newport, producing alteration of membrane permeability and disruption of the subsequent gradient dissipation, which inhibits several processes essential for cell viability, such as oxygen consumption. Induces bacterial filamentation in susceptible cells in a non-SOS-dependent way, but this phenotype may result from impaired transcription of genes coding for cell division proteins.<ref>PMID:11731133</ref> <ref>PMID:11443089</ref> <ref>PMID:12401787</ref>
-The line below this paragraph, {{ABSTRACT_PUBMED_15096038}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 15096038 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_15096038}}
 ==About this Structure==
@@ Line 22: / Line 10: @@
 ==Reference==
-<ref group="xtra">PMID:015096038</ref><references group="xtra"/>
+<ref group="xtra">PMID:015096038</ref><references group="xtra"/><references/>
 [[Category: Escherichia coli]]
 [[Category: Afonso, C.]]