3oq1: Difference between revisions
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[[Image:3oq1.png|left|200px]] | [[Image:3oq1.png|left|200px]] | ||
{{STRUCTURE_3oq1| PDB=3oq1 | SCENE= }} | {{STRUCTURE_3oq1| PDB=3oq1 | SCENE= }} | ||
===Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor=== | ===Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor=== | ||
{{ABSTRACT_PUBMED_20971000}} | {{ABSTRACT_PUBMED_20971000}} | ||
==About this Structure== | ==About this Structure== | ||
[[3oq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ1 OCA]. | [[3oq1]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ1 OCA]. | ||
==See Also== | |||
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | |||
==Reference== | ==Reference== | ||
Revision as of 10:55, 25 July 2012
Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor
Template:ABSTRACT PUBMED 20971000
About this Structure
3oq1 is a 4 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yan X, Wang Z, Sudom A, Cardozo M, DeGraffenreid M, Di Y, Fan P, He X, Jaen JC, Labelle M, Liu J, Ma J, McMinn D, Miao S, Sun D, Tang L, Tu H, Ursu S, Walker N, Ye Q, Powers JP. The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7071-5. Epub 2010 Sep 29. PMID:20971000 doi:10.1016/j.bmcl.2010.09.097