3t0m: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3t0m|  PDB=3t0m  |  SCENE=  }}
===Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening===
{{ABSTRACT_PUBMED_23939230}}


The entry 3t0m is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.


Authors: Thiel, P., Ottmann, C.
==About this Structure==
[[3t0m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0M OCA].  


Description: Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening
==Reference==
<ref group="xtra">PMID:023939230</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Ottmann, C.]]
[[Category: Thiel, P.]]
[[Category: Adapter protein]]
[[Category: Helical protein]]
[[Category: Protein binding-inhibitor complex]]
[[Category: Protein-protein interaction]]
Retrieved from "https://proteopedia.org/3t0m"