Pal: Difference between revisions

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{{STRUCTURE_1oap | PDB=1oap | SCENE= Periplasmic_Domain_of_Pal/Palperiplasmicdomain/1 }}

==Structure==

Pal is a lipoprotein which is anchored in the outer membrane with an approximate length of 173 amino acids in the precursor form. It contains a signal sequence including an LVAC motif, with the flexible, hydrophobic N-terminal tail binding to the inner leaflet of the outer membrane and anchoring it. During translocation, signal peptidase II cleaves the LVAC motif, and the localisation of Pal is dependent on the Lol protein system. Serine, the amino acid at #2 position in the mature protein is a localisation determinant for the position of Pal in the outer membrane<ref name='Godlewska'>PMID: 19519769</ref>. The periplasmic domain of Pal can be seen in the 3D structure 1OAP.

'''Pal''' is a lipoprotein which is anchored in the outer membrane with an approximate length of 173 amino acids in the precursor form. It contains a signal sequence including an LVAC motif, with the flexible, hydrophobic N-terminal tail binding to the inner leaflet of the outer membrane and anchoring it. During translocation, signal peptidase II cleaves the LVAC motif, and the localisation of Pal is dependent on the Lol protein system. Serine, the amino acid at #2 position in the mature protein is a localisation determinant for the position of Pal in the outer membrane<ref name='Godlewska'>PMID: 19519769</ref>. The periplasmic domain of Pal can be seen in the 3D structure 1OAP.

==Function==

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 {{STRUCTURE_1oap |  PDB=1oap  |  SCENE= Periplasmic_Domain_of_Pal/Palperiplasmicdomain/1 }}
 ==Structure==
-Pal is a lipoprotein which is anchored in the outer membrane with an approximate length of 173 amino acids in the precursor form.  It contains a signal sequence including an LVAC motif, with the flexible, hydrophobic N-terminal tail binding to the inner leaflet of the outer membrane and anchoring it.  During translocation, signal peptidase II cleaves the LVAC motif, and the localisation of Pal is dependent on the Lol protein system.  Serine, the amino acid at #2 position in the mature protein is a localisation determinant for the position of Pal in the outer membrane<ref name='Godlewska'>PMID: 19519769</ref>.  The periplasmic domain of Pal can be seen in the 3D structure 1OAP.
+'''Pal''' is a lipoprotein which is anchored in the outer membrane with an approximate length of 173 amino acids in the precursor form.  It contains a signal sequence including an LVAC motif, with the flexible, hydrophobic N-terminal tail binding to the inner leaflet of the outer membrane and anchoring it.  During translocation, signal peptidase II cleaves the LVAC motif, and the localisation of Pal is dependent on the Lol protein system.  Serine, the amino acid at #2 position in the mature protein is a localisation determinant for the position of Pal in the outer membrane<ref name='Godlewska'>PMID: 19519769</ref>.  The periplasmic domain of Pal can be seen in the 3D structure 1OAP.
 ==Function==