335d: Difference between revisions

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==Overview==

The crystal structure of the decamer d(GGCAATTGCG) has been determined at, 2.4 A resolution. The central eight bases of each DNA single-strand base, pair with a self-complementary strand to form an octamer B-DNA duplex., These duplexes lie end-to-end within the unit cell. The terminal 5'-G and, G-3' bases of each decamer strand are unpaired, and interact with the, neighbouring duplexes via interactions within both the major and minor, groove. This results in base triplets of the type G-(G.C) and G*(G.C), with the third guanine base binding to a Watson-Crick G.C base pair from, the major groove and the minor groove, respectively. The triplet, interaction of the type G-(G.C) involves Hoogsteen hydrogen-bonding, interactions between the two guanine bases. The minor- and major-groove, base triplet interactions which exist within this structure act to, stabilize the d(GCAATTGC)2 B-DNA octamer duplex.

The crystal structure of the decamer d(GGCAATTGCG) has been determined at 2.4 A resolution. The central eight bases of each DNA single-strand base pair with a self-complementary strand to form an octamer B-DNA duplex. These duplexes lie end-to-end within the unit cell. The terminal 5'-G and G-3' bases of each decamer strand are unpaired, and interact with the neighbouring duplexes via interactions within both the major and minor groove. This results in base triplets of the type G-(G.C) and G*(G.C), with the third guanine base binding to a Watson-Crick G.C base pair from the major groove and the minor groove, respectively. The triplet interaction of the type G-(G.C) involves Hoogsteen hydrogen-bonding interactions between the two guanine bases. The minor- and major-groove base triplet interactions which exist within this structure act to stabilize the d(GCAATTGC)2 B-DNA octamer duplex.

==About this Structure==

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[[Category: Protein complex]]

[[Category: Neidle, S.]]

[[Category: Nunn, C.M.]]

[[Category: Nunn, C M.]]

[[Category: MG]]

[[Category: a-dna]]

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[[Category: flipped-out base]]

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@@ Line 4: / Line 4: @@
 ==Overview==
-The crystal structure of the decamer d(GGCAATTGCG) has been determined at, 2.4 A resolution. The central eight bases of each DNA single-strand base, pair with a self-complementary strand to form an octamer B-DNA duplex., These duplexes lie end-to-end within the unit cell. The terminal 5'-G and, G-3' bases of each decamer strand are unpaired, and interact with the, neighbouring duplexes via interactions within both the major and minor, groove. This results in base triplets of the type G-(G.C) and G*(G.C), with the third guanine base binding to a Watson-Crick G.C base pair from, the major groove and the minor groove, respectively. The triplet, interaction of the type G-(G.C) involves Hoogsteen hydrogen-bonding, interactions between the two guanine bases. The minor- and major-groove, base triplet interactions which exist within this structure act to, stabilize the d(GCAATTGC)2 B-DNA octamer duplex.
+The crystal structure of the decamer d(GGCAATTGCG) has been determined at 2.4 A resolution. The central eight bases of each DNA single-strand base pair with a self-complementary strand to form an octamer B-DNA duplex. These duplexes lie end-to-end within the unit cell. The terminal 5'-G and G-3' bases of each decamer strand are unpaired, and interact with the neighbouring duplexes via interactions within both the major and minor groove. This results in base triplets of the type G-(G.C) and G*(G.C), with the third guanine base binding to a Watson-Crick G.C base pair from the major groove and the minor groove, respectively. The triplet interaction of the type G-(G.C) involves Hoogsteen hydrogen-bonding interactions between the two guanine bases. The minor- and major-groove base triplet interactions which exist within this structure act to stabilize the d(GCAATTGC)2 B-DNA octamer duplex.
 ==About this Structure==
@@ Line 13: / Line 13: @@
 [[Category: Protein complex]]
 [[Category: Neidle, S.]]
-[[Category: Nunn, C.M.]]
+[[Category: Nunn, C M.]]
 [[Category: MG]]
 [[Category: a-dna]]
@@ Line 19: / Line 19: @@
 [[Category: flipped-out base]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:35:45 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:02:05 2008''