1oey: Difference between revisions

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[[Image:1oey.png|left|200px]]
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{{STRUCTURE_1oey|  PDB=1oey  |  SCENE=  }}  
{{STRUCTURE_1oey|  PDB=1oey  |  SCENE=  }}  
===HETERODIMER OF P40PHOX AND P67PHOX PB1 DOMAINS FROM HUMAN NADPH OXIDASE===
===HETERODIMER OF P40PHOX AND P67PHOX PB1 DOMAINS FROM HUMAN NADPH OXIDASE===
{{ABSTRACT_PUBMED_12887891}}


==Disease==
[[http://www.uniprot.org/uniprot/NCF4_HUMAN NCF4_HUMAN]] Defects in NCF4 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 3 (CGD3) [MIM:[http://omim.org/entry/613960 613960]]. CGD3 is a disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.<ref>PMID:19692703</ref>


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_12887891}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/NCF4_HUMAN NCF4_HUMAN]] Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.
(as it appears on PubMed at http://www.pubmed.gov), where 12887891 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12887891}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:012887891</ref><references group="xtra"/>
<ref group="xtra">PMID:012887891</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gill, D J.]]
[[Category: Gill, D J.]]