1e1y: Difference between revisions

Revision as of 15:42, 25 July 2012

1e1y is a 1 chain structure of Glycogen Phosphorylase with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Oikonomakos NG, Schnier JB, Zographos SE, Skamnaki VT, Tsitsanou KE, Johnson LN. Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site. J Biol Chem. 2000 Nov 3;275(44):34566-73. PMID:10924512 doi:https://dx.doi.org/10.1074/jbc.M004485200
Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate. Protein Sci. 1999 Oct;8(10):1930-45. PMID:10548038
Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure. 1997 Nov 15;5(11):1413-25. PMID:9384557

@@ Line 1: / Line 1: @@
 [[Image:1e1y.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_1e1y", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_1e1y|  PDB=1e1y  |  SCENE=  }}
 ===FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_10924512}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10924512 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_10924512}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Glycogen Phosphorylase]]
+*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
 ==Reference==