1cwh: Difference between revisions

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==Overview==
==Overview==
Eight new X-ray structures of different cyclophilin, A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide, a useful structural database for the analysis of protein-ligand, interactions. The effect of small chemical differences on protein-ligand, hydrogen-bonding, van der Waals interactions and water structure is, presented.
Eight new X-ray structures of different cyclophilin A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide a useful structural database for the analysis of protein-ligand interactions. The effect of small chemical differences on protein-ligand hydrogen-bonding, van der Waals interactions and water structure is presented.


==About this Structure==
==About this Structure==
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[[Category: Mikol, V.]]
[[Category: Mikol, V.]]
[[Category: Taylor, P.]]
[[Category: Taylor, P.]]
[[Category: Walkinshaw, M.D.]]
[[Category: Walkinshaw, M D.]]
[[Category: complex (isomerase/immunosuppressant)]]
[[Category: complex (isomerase/immunosuppressant)]]


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