Urokinase: Difference between revisions
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Michal Harel (talk | contribs) New page: {{STRUCTURE_3ig6| PDB=3ig6 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, 3ig6 }} '''Urokinase''' (UK) is a serine protease whose principa... |
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{{STRUCTURE_3ig6| PDB=3ig6 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, [[3ig6]] }} | {{STRUCTURE_3ig6| PDB=3ig6 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, [[3ig6]] }} | ||
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== 3D Structures of urokinase == | == 3D Structures of urokinase == | ||
[[2i9a]] - hUK Hc N terminal | |||
===Urokinase heavy chain complex with inhibitors=== | |||
[[1fv9]] – hUK B chain (mutant) + benzimidazole derivative – human<br /> | |||
[[1f5k]] - hUK B chain (mutant) + benzamidine derivative<br /> | |||
[[1f5l]] - hUK B chain (mutant) + amiloride derivative<br /> | |||
[[1f92]], [[1sc8]], [[1vj9]], [[1vja]], [[2o8t]], [[2o8u]], [[2o8w]] - hUK B chain (mutant) + inhibitor<br /> | |||
[[1owd]], [[1owe]], [[1owh]], [[1owi]], [[1owj]], [[1owk]], [[1sqa]], [[1sqo]], [[1u6q]] - hUK B chain + naphthamidine inhibitor<br /> | |||
[[1ejn]] - hUK B chain (mutant) + urea derivative inhibitor<br /> | |||
[[3kpg]] – hUK Hc C terminal (mutant) + benzoic acid derivative<br /> | |||
[[3khv]] - hUK Hc C terminal (mutant) + methanol derivative<br /> | |||
[[3mwi]] - hUK Hc C terminal (mutant) + amidine derivative<br /> | |||
[[3ox7]], [[3oy5]], [[3oy6]] - hUK Hc C terminal (mutant) + peptide inhibitor<br /> | |||
[[3kid]], [[3mhw]] - hUK Hc C terminal (mutant) + aminobenzothiazole derivative<br /> | |||
[[2vin]], [[2vio]], [[2vip]], [[2viq]], [[2viv]], [[2viw]] - hUK B chain catalytic domain (mutant) + mexiletine derivative<br /> | |||
[[2vnt]], [[2r2w]] - hUK B chain catalytic domain + guanidine derivative<br /> | |||
[[1w0z]], [[1w10]], [[1w11]], [[1w12]], [[1w13]], [[1w14]] - hUK B chain catalytic domain + alanineamide derivative<br /> | |||
[[2nwn]] - hUK Hc C terminal + cyclic peptide<br /> | |||
[[3m61]] - hUK Hc C terminal (mutant) + cyclic peptide | |||
===Urokinase light+heavy chain complex with inhibitors=== | |||
[[1lmw]] – hUK A+B catalytic domain + EGRCMK<br /> | |||
[[1c5w]], [[1c5x]], [[1c5y]], [[1c5z]] - hUK A+B chain catalytic domain + carboxamidine derivative<br /> | |||
[[1gi7]], [[1gi8]], [[1gi9]], [[1gj7]], [[1gj8]], [[1gj9]], [[1gja]], [[1gjb]], [[1gjc]], [[1gjd]] - hUK A+B chain catalytic domain (mutant) + carboxamidine derivative<br /> | |||
[[1o3p]], [[1o5a]], [[1o5b]], [[1o5c]] - hUK A+B chain catalytic domain (mutant) + benzenolate derivative<br /> | |||
[[3ig6]] – hUK A+B chain catalytic domain + inhibitor<br /> | |||
===Urokinase complex with protein=== | |||
[[2fd6]] – hUK Hc N terminal + antibody + UK receptor<br /> | |||
[[3bt1]], [[3bt2]] - hUK Hc N terminal + vitronectin + UK receptor<br /> | |||
[[3laq]] - hUK Hc N terminal + UK receptor<br /> | |||
[[3pb1]] - hUK Hc C terminal (mutant) + UK inhibitor<br />-1 | |||
[[2i9b]] - hUK Hc N terminal + UK receptor (mutant) | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
