1e4e: Difference between revisions
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m Protected "1e4e" [edit=sysop:move=sysop] |
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{{STRUCTURE_1e4e| PDB=1e4e | SCENE= }} | {{STRUCTURE_1e4e| PDB=1e4e | SCENE= }} | ||
===D-ALANYL-D-LACATE LIGASE=== | ===D-ALANYL-D-LACATE LIGASE=== | ||
{{ABSTRACT_PUBMED_10908650}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VANA_ENTFC VANA_ENTFC]] Required for high-level resistance to glycopeptide antibiotics. D-Ala--D-Ala ligase of altered specificity which catalyzes ester bond formation between D-Ala and various D-hydroxy acids; produces a peptidoglycan which does not terminate in D-alanine but in D-lactate, thus preventing vancomycin or teicoplanin binding.<ref>PMID:1931965</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010908650</ref>< | <ref group="xtra">PMID:010908650</ref><references group="xtra"/><references/> | ||
[[Category: Enterococcus faecium]] | [[Category: Enterococcus faecium]] | ||
[[Category: Roper, D I.]] | [[Category: Roper, D I.]] | ||