Urokinase: Difference between revisions

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{{STRUCTURE_3ig6|  PDB=3ig6 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, [[3ig6]] }}
{{STRUCTURE_1fv9|  PDB=1fv9 | SIZE=400| SCENE= |right|CAPTION=Human urokinase A and B chains complex with inhibitor, [[1fv9]] }}


'''Urokinase''' (UK) is a serine protease whose principal substrate is plasminogen – the inactive zymogen of plasmin.  UK consists of 3 domains: ligand-binding domain and kringle and growth factor domains.  Prourokinase (PUK) is the inactive zymogen of UK which becomes active by proteolytic cleavage.
'''Urokinase''' (UK) is a serine protease whose principal substrate is plasminogen – the inactive zymogen of plasmin.  UK consists of 3 domains: ligand-binding domain and kringle and growth factor domains.  Prourokinase (PUK) is the inactive zymogen of UK which becomes active by proteolytic cleavage.